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Il y a 244 citations sur le ITS.
This in vitro study aims to evaluate the effectiveness of silver diamine fluoride and Potassium iodide (SDF-KI) in comparison to casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) varnish, sodium fluoride (NaF) varnish, silver diamine fluoride (SDF) alone and deionized water as a control group in the prevention of dental erosion in primary teeth and assessing its staining effect. Nature — Effect of silver diamine fluoride/potassium iodide treatment on the prevention of dental erosion in primary teeth: an in vitro study | BDJ Open
While not wavering in its belief that there was not full-scale lewisite production in Willoughby, the Corps last month included $100,000 in its current budget for an archived photographic analysis and historical site assessment of the location this year. News-Herald — Willoughby’s war history coming into focus – News-Herald
Scientists on NASA's EMIT mission used data from its powerful imaging spectrometer, developed at the agency's Jet Propulsion Laboratory, to map the presence and geographic distributions of three key minerals in the planet's arid regions. The three substances – hematite, goethite, and kaolinite – are thought to have an effect on atmospheric and surface temperatures when wind lofts them into the air, forming dust storms. NASA Jet Propulsion Laboratory (JPL) — NASA's EMIT Mission Produces Maps of Arid Region Surface Minerals
The candles are housed in a keepsake glass bowl inspired by the colours of its corresponding fragrance bottle Harry Styles’ sex-inspired fragrances are now available as candles
In ancient times, the purity of precious metals was gauged using a touchstone: a small tablet of dark fieldstone, slate or lyddite on whose finely grained surface soft metals such as gold left a visible trace. From its earliest known use by the Harappan civilisation of the Indus Valley, this simple test of authenticity travelled to Europe and beyond, its symbolism as well as its practical application intriguing philosophers of every epoch, from classical Greece to the modern era. Frontline — Palestine, the touchstone for Western morality - Frontline
The longitudinal population studies strategic advisory panel (LPS-SAP, previously the cohort strategic review group) assists MRC in delivering its strategic objective of maximising the impact of population health studies. Longitudinal population studies strategic advisory panel – UKRI
Through the fourth amendment to the Patent Law of China in 2020, China established its own pharmaceutical patent linkage system. In December 2021, the Beijing Intellectual Property Court accepted the first pharmaceutical patent linkage lawsuit and issued its decision on April 15, 2022. This presentation will discuss China’s new pharmaceutical patent linkage system, including the legislative process and its current operation in practice. Topics will cover: China's Pharmaceutical Patent Linkage System | Insights | Mayer Brown
Archaeologists found a huge amount of litharge - a lead oxide and by-product of silver extraction - which suggests a clan was melting down metal to get at its precious material. Mail Online — Treasures of ancient crypt could be home to largest illegal silversmithing site in Roman Britain | Daily Mail Online
ORF3a blocked the retrieval of CI-M6PR from Rab7-positive endosomes to the TGN and, consequently, impaired the sorting of newly synthesized lysosomal hydrolases from the TGN. ORF3a expression and SARS-CoV-2 infection also impaired the fusion of Rab7-positive compartments with Arl8b and LAMP1-positive compartments that mediate virus egress from host cells. Taken together, our results suggest that SARS-CoV-2, through its accessory protein ORF3a, blocks Rab7 GTP-GDP cycling, which impairs lysosome fusion with other compartments and rather promotes the egress of the virus via lysosomal exocytosis. Nature — SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle | Nature Communications
Investors are coming to similar conclusions about other macrocycle firms. The California start-up Insamo recently announced that it has secured $12 million in seed funding to develop small, orally available and cell-permeable cyclic peptides using artificial intelligence protein design expertise. The UK start-up Curve Therapeuticsjust raised about $52 million in series A funding for what it calls its “microcycle” platform. Chemical & Engineering News — Macrocycle start-ups emerge from stealth
The California-based biotech uses its combination of AI and chemistry expertise to “address the complexities of medicinal chemistry in the macrocycle space,” the company said in a Jan. 23 release. Now, Merck has tapped up UNP to apply its tech to develop macrocyclic candidates against a “challenging” undisclosed oncology target. Fierce Biotech — Merck & Co. signs $220M macrocyclic peptide deal
Nissan has committed at least an additional four years to the ABB FIA Formula E World Championship until 2030, continuing its manufacturer outfit into the GEN4 era. The Official Home of Formula E — Nissan becomes first manufacturer to commit to Formula E GEN4
Cependant, c’est le physicien Hideki Yukawa qui, en 1934, dans un article intitulé « Meson theory in its development », propose un modèle d’interaction entre nucléons faisant intervenir un boson particulier : le méson. Quelques temps plus tard, en 1939, l’expérimentation lui donnera raison et attribuera son nom au potentiel attaché à la liaison nucléon-nucléon : le potentiel de Yukawa. Dans les années suivantes, les modèles mésoniques se développeront, notamment sous l’impact de la chromodynamique quantique, et contribueront à décrire de manière plus précise les schémas d’interaction mésonique entre nucléons. Trust My Science — Comment les nucléons sont-ils liés dans le noyau atomique ?
The prospect of a mini miter saw that promises to deliver on both fronts was compelling enough to lead me to conduct a thorough examination of its capabilities. Here’s a detailed exploration of what I discovered about the BEAMNOVA Mini Miter Saw, from its design and functionality to its performance and overall value. Forestry Editorial — BEAMNOVA Mini Miter Saw Electric Power Table Saw Review - Forestry Reviews
A government advisory for farmers that was issued recently prescribed potash spray to manage the standing wheat crop from high temperatures. However, a skewed fertiliser subsidy policy in favour of urea and di-ammonium phosphate (DAP) has made muriate of potash (MoP) out of reach from small and marginal farmers with its sales dropping by over 37 per cent in the current fiscal. BusinessLine — Muriate of Potash sales down due to lower govt subsidy - The Hindu BusinessLine
But the community, and its individuals, face unique challenges and stresses. According to the ADA, multiracial individuals “face mental health challenges including anxiety, depression and the imposter syndrome.” Campus Echo Online - N.C. Central University's Student Newspaper — ‘Who am I?’ The biracial POV - Campus Echo Online
“We continue to identify new mechanisms by which nitrases are implicated in diseases, and these recent nitro-protein data analyses support the use of nitrase-based targets as a truly novel therapeutic approach to cancer treatment,” said Irene Griswold-Prenner, Ph.D., chief scientific officer of Nitrase Therapeutics. “The data have elucidated numerous, specific, actionable targets for possible therapeutic intervention. We look forward to continued evaluation of protein nitration and its enzymatic regulation as a new path to drug discovery for cancer and other diseases areas.” GlobeNewswire News Room — Nitrase Therapeutics Announces Publication in the Journal
In a circular issued today, the KPDCL directed all its subordinate offices to immediately enforce the ban that was announced in February 2018. The ban prohibits manufacture, import, transport, sale, purchase or use of nichrome coil-based crude heaters, boilers and steamers as they do not meet the specifications prescribed by the Bureau of Indian Standards (BIS) or the International Electrotechnical Commission. Greater Kashmir — Use of nichrome-wire crude heaters | KPDCL for strict implementation of ban - Greater Kashmir
Samsung has now released its One Hand Operation app on the Google Play Store which brings the gesture-based nivation functions. This new implementation from the South Korean giant completely hides the bottom navigation bar and uses swipes/gestures instead. MobiGyaan — Samsung's One Hand Operation + gesture navigation app is now available on Play Store
Although some nomenclatural problems will still need to be addressed in the future, this monograph, the largest of its kind in the zoological literature, will hopefully go a long way towards achieving the long-term stability of names used in beetle higher classification. EurekAlert! — 'Family-Group Names in Coleoptera (Insecta)' | EurekAlert!