Accueil > Citations > Citations sur le AND

Citations sur le AND

Il y a 2452 citations sur le AND.

• As well as the obvious danger of bombs, many of the female munitions workers suffered illnesses which later proved fatal, caused by exposure to lyddite and amatol explosives.

• PRINCETON, N.J. - Bristol Myers Squibb (NYSE: BMY) a annoncé aujourd'hui que la Food and Drug Administration (FDA) américaine a accordé une autorisation accélérée à Breyanzi (lisocabtagene maraleucel ; liso-cel), une thérapie cellulaire CAR (chimeric antigen receptor) dirigée contre le CD19. Cette autorisation permet le traitement de patients adultes atteints de leucémie lymphocytaire chronique (LLC) ou de lymphome lymphocytaire de petite taille (SLL) en rechute ou réfractaire, ayant reçu au moins deux traitements antérieurs, dont un inhibiteur de la tyrosine kinase de Bruton (BTK) et un inhibiteur du lymphome à cellules B 2 (BCL-2).

• ORF3a blocked the retrieval of CI-M6PR from Rab7-positive endosomes to the TGN and, consequently, impaired the sorting of newly synthesized lysosomal hydrolases from the TGN. ORF3a expression and SARS-CoV-2 infection also impaired the fusion of Rab7-positive compartments with Arl8b and LAMP1-positive compartments that mediate virus egress from host cells. Taken together, our results suggest that SARS-CoV-2, through its accessory protein ORF3a, blocks Rab7 GTP-GDP cycling, which impairs lysosome fusion with other compartments and rather promotes the egress of the virus via lysosomal exocytosis.

• They said that only earth work was carried on the road and after the passage of over eight years no macadamisation or other repair work has been taken up.

• Investors are coming to similar conclusions about other macrocycle firms. The California start-up Insamo recently announced that it has secured $12 million in seed funding to develop small, orally available and cell-permeable cyclic peptides using artificial intelligence protein design expertise. The UK start-up Curve Therapeuticsjust raised about $52 million in series A funding for what it calls its “microcycle” platform.

• The California-based biotech uses its combination of AI and chemistry expertise to “address the complexities of medicinal chemistry in the macrocycle space,” the company said in a Jan. 23 release. Now, Merck has tapped up UNP to apply its tech to develop macrocyclic candidates against a “challenging” undisclosed oncology target.

• "All you ever wanted was to be a mammy and what an amazing mammy you were.

• A “realistic” obese manakin has been developed to help educate further nurses and healthcare professionals.

• The business manganate has kept his salary capped at Rs 15 crore since 2008-09 forgoing commission of nearly Rs 24 crore annually. In comparison, other directors and top executive at the company saw handsome raise in their annual salary at the financial year ending on March 31, 2018.

• Prodi, A. et al. Charge, orbital and spin ordering phenomena in the mixed valence manganite (NaMn3 3+)(Mn2 3+Mn2 4+)O12. Nat. Mater. 3, 48–52 (2004).

• Dairy milk production has increased manifold in eastern Nangarhar province this year due to growing number of dairy farms and proper feeding, Canal Project officials . . .

• The Manorial Society aims to promote the study of English history and traditions, especially the monarchy and British parliamentary institutions and the preservation of manorial records.

• Exploiting ancient manorial rights in Britain to go hunting, fishing and shooting over other people’s land, could soon be outlawed, MPs have suggested.

• In a recent report, the Commons’ All-Party Justice Select Committee called on the Government’s legal advisers to review the operation of manorial rights. The report said there were fears homeowners could be saddled with significant legal fees over disputed manorial claims, which could also delay property sales, and potentially affect house prices.

• Farmer William Brown’s attempt to register manorial rights over Aldbourne sports field and Palmers Field has met opposition from the parish council.

• Former Miami Dolphin and NFL star Vontae Davis was found dead inside a Southwest Ranches mansion on Monday, authorities said.

• We knew that marcescence had been relatively well researched in arid ecosystems, in which solar radiation strongly degrades difficult-to-decompose compounds in retained biomass. This facilitates decomposition of and nutrient release from that biomass once shed, with potential competitive advantages for the respective plants.

• Akashi, H., Okamura, E., Nishihama, R., Kohchi, T. & Hirai, M. Y. Identification and biochemical characterization of the serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase in marchantia polymorpha. Front. Plant Sci. 9 (2018).

• Ishizaki, K., Nishihama, R., Yamato, K. T. & Kohchi, T. Molecular genetic tools and techniques for marchantia polymorpha research. Plant Cell Physiol. 57, 262–270 (2016).

• Max became margrave — which Debrett's defines as the German rank of count — upon his father's death, and was instrumental in the revitalization of Lake Constance land which led to the flourishing Markgraf von Baden winery.