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Citations sur le AND

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• Protalix has partnered with Chiesi Farmaceutici S.p.A. for the global development and commercialization of Elfabrio. Protalix's development pipeline consists of proprietary versions of recombinant therapeutic proteins that target established pharmaceutical markets, including the following product candidates: PRX–115, a plant cell-expressed recombinant PEGylated uricase for the treatment of severe gout; PRX–119, a plant cell-expressed long action DNase I for the treatment of NETs-related diseases; and others.

• i) uridine phosphorylase 1 (UPP1)/UPP2-catalyzed phosphorolytic cleavage of uridine into uracil and ribose-1-phosphate (R1P);

• The first-in-class uridine phosphorylase inhibitor TK-90 almost completely eliminated severe oral mucositis (SOM) in patients with non-metastatic squamous cell carcinoma of the head and neck who underwent radiation therapy, a small randomized study showed.

• As a researcher in Mootha's lab, Jourdain wanted to know which genes and pathways cells might use to stay alive when nutrients are limited. Using a genetic screen, Jourdain and his colleagues found that the expression of two genes, UPP1 and UPP2, dramatically increases the growth of cells in media without glucose. These genes encode enzymes that help break down uridine, and cells expressing UPP1 and UPP2 grew when uridine was their only food source.

• Using five to 10 feathers from the dead birds’ necks and cutting out their “dye” secreting uropygial glands, they tested if the sun really did have this bleaching effect on their feathers. They popped a bunch of feathers on the roof while others were kept in the dark and assessed how their color had changed over 40 days.

• Birds look disheveled and unrecognisable as they vigorously clean their plumes. These painting and polishing sessions of birds are part of their grooming routines. Most birds do this several times a day. Called preening, it involves digging the bill into the base of the body close to the tail to take out a greasy substance called preen oil from the uropygial gland. Then, the bird sets about coating the feathers with the oil to keep them strong and flexible.

• Prosalirus, discovered by Neil Shubin of the University of Pennsylvania in Philadelphia and Farish Jenkins of Harvard University, seems to be a relative of Triadobatrachus. But its sacral ribs and urostyle are almost indistinguishable from a modern frog’s (Nature, vol 377, p 49). “If you saw it hopping around in your back yard, you wouldn’t think much of it,” says Robert Carroll, an amphibian palaeontologist at McGill University in Montreal.

• Ricky Martin and his twins, Matteo and Valentino, enjoy their vacation in Japan

• The summer vacations usually take place in early May or mid-May, depending on different schools’ personal timetable. The summer vacations usually last till mid-June, after which schools reopen and regular classes are resumed. The summer vacation may or may not get extended depending on the weather conditions.

• Pharmaceutical giant being sued in class action over claims its vaccine caused death and serious injury in dozens of cases

• And he added: “The years in which we were unelectable, the years when our promises could not be turned into reality, the years when we were mired in vacillation at best and obscuring at worst of antisemitism, have been put behind us. 

• A team led by Prof. Guang Shouhong and Prof. Feng Xuezhu from the University of Science and Technology (USTC) of the Chinese Academy of Sciences (CAS) revealed, for the first time, the composition and regulatory mechanism of the nuclear vacuole in C. elegans. The study was published in Cell Reports.

• The branched chain amino acids (BCAA) leucine, isoleucine, and valine are essential nutrients that have been associated with diabetes, cancers, and cardiovascular diseases. Observational studies suggest that BCAAs exert homogeneous phenotypic effects, but these findings are inconsistent with results from experimental human and animal studies.

• Epos Now's lofty valuation target highlights the optimistic market expectations for tech companies offering integral business solutions. This move could become a reference point for valuation in similar future deals, potentially reshaping investor perspectives and market dynamics.

• Kenneth Price, Hillegass Professor of English and the center’s co-director, has earned a three-year, $300,000 grant from the National Endowment for the Humanities to examine at least 20 copies of the original 1855 edition of “Leaves of Grass.” The CDRH will start a digital variorum – a collection containing different versions of the text – on the Walt Whitman Archive. When completed, the project will record and provide background on each variation.

• “I think it will be illuminating for readers and scholars,” said Price. Not only will the variorum highlight differences between different copies of the first edition, it will contain contextual links that make it easy to compare how one line migrated from the manuscript to an often entirely different place within the printed poem. “He seems to have thought of the line as his unit of composition,” said Price, who referred to Whitman’s habit of moving lines from place to place as “a sort of proto word processing.”

• Le dermatologue tunisien, Moez Ben Salem, membre de la société tunisienne de dermatologie et de vénérologie (STDV) a été nommé vendredi président de la société africaine de dermatologie et de vénérologie (African Society of Dermatology and Venereology- ASDV) pour un mandat de deux ans et ce, à l’issue de l’assemblée générale de la société savante tenue en marge du 4ème congrès africain de dermatologie et de vénérologie organisé du 23 au 27 avril en cours au palais des congrès à Tunis

• There's a French slang called verlan where you invert a word's syllables (e.g. bonjour becomes "jourbon" and français becomes "céfran"). Pageviews for the verlan Wikipedia article SPIKED when a French Barbie poster used verlan to say "She's everything. He only knows how to fuck" pic.twitter.com/JkmyeFwAad

• Associated Press photographers documented violence and vibrance throughout Latin America in 2023, creating vivid portraits of ability to keep moving forward despite suffering.

• The RBV sensor utilized vidicon tube instruments containing an electron gun that read images from a photoconductive faceplate similar to television cameras. The data stream received from the satellite was analog-to-digital preprocessed to correct for radiometric and geometric errors.