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Source 1 : Julie Lacombe et al, Vitamin K-dependent carboxylation regulates Ca2 + flux and adaptation to metabolic stress in β cells, Cell Reports (2023). DOI : 10.1016/j.celrep.2023.112500
Santé Magazine — Vitamine K : des chercheurs montrent comment elle aide à prévenir le diabète | Santé Magazine -
Alabaster, A. et al. Deficiencies in acetyl-CoA carboxylase and fatty acid synthase 1 differentially affect eggshell formation and blood meal digestion in Aedes aegypti. Insect Biochem. Mol. Biol. 41, 946–955 (2011).
Nature — RNAi knockdown of acetyl-CoA carboxylase gene eliminates jinggangmycin-enhanced reproduction and population growth in the brown planthopper, Nilaparvata lugens | Scientific Reports -
The researchers generated wheat germplasms harboring herbicide tolerance mutations that confer tolerance to sulfonylurea-, imidazolinone- and aryloxyphenoxy propionate-type herbicides by base editing the acetolactate synthase (ALS) and acetyl-coenzyme A carboxylase genes of commercial wheat cultivar Kenong199.
EurekAlert! — CRISPRed wheat helps farmers control weeds | EurekAlert! -
Dr Stephen Hodges, Lead Investigator presented 'A vitamin K catabolite regulates Wnt 16-mediated B-catenin activation leading to increased osteoblast proliferation, with enhanced expression of osteocalcin and osteoprotegrin'.
BioSpace — Haoma Medica Announces Late-Breaking Science Results for Naquinate, as a New Way to Support Bone Health and Healthy Aging, at the ASBMR 2022 Annual Meeting | BioSpace -
Les archéologues ont fouillé les restes de cette catapulte en amont des travaux de construction du Harwell Science and Innovation Campus, un ensemble de groupes de recherche gouvernementaux, universitaires et industriels. Ces investigations ont permis de révéler le fonctionnement interne de cette catapulte unique en son genre.
Sciencepost — Une catapulte conçue pour lancer des bombardiers de la Seconde Guerre mondiale découverte en Angleterre -
«La création de «Love and Titanium» a été douloureuse, profondément curative et finalement cathartique pour moi», confie Jeremy Renner.
Le Matin — Après son grave accident, Jeremy Renner sort des chansons sur sa convalescence - Le Matin -
Changizi, R., Zaefferer, S., Abdellaoui, L. & Scheu, C. Effects of defect density on optical properties using correlative cathodoluminescence and transmission electron microscopy measurements on identical PrNbO4 particles. ACS Appl. Electron. Mater. 4(4), 2095–2100 (2022).
Nature — Combined structural analysis and cathodoluminescence investigations of single Pr3+-doped Ca2Nb3O10 nanosheets | Scientific Reports -
"However, the expensive precursor and complex synthesis process hinders exploration of cathode electrode/electrolyte interfaces and solvation structures. We developed a universal cation replacement method to prepare low-cost, high-reversibility magnesium and calcium electrolytes derived from a zinc organoborate solvation structure."
A cation replacement method to realize highly performing electrolytes for multivalent metal batteries -
On December 1, 2023, amendments to Federal Rule of Evidence (FRE) 702 geared toward emphasizing and explaining the responsibility of the judge as a “gatekeeper” for expert testimony took effect. On December 18, 2023, one of the first decisions to include an analysis under amended FRE 702 featured a New York federal judge fulfilling that gatekeeper role in granting defendants’ motions to exclude all five of plaintiffs’ experts’ causation opinions in the Acetaminophen ASD-ADHD product liability multi-district litigation (MDL) (In re: Acetaminophen – ASD-ADHD Products Liability Litigation, Case 1:22-md-03043-DLC).
Foley & Lardner LLP — Acetaminophen MDL: Judge Excludes All of Plaintiffs’ Causation Experts Pursuant to Newly-Amended FRE Rule 702 | Foley & Lardner LLP -
François, professeur de danses sportives/société, et Françoise Foulquier invitent le public pour un nouveau stage de danses latines (danses de couple), ce samedi 13 janvier, à la salle Concept Form à Decazeville (parking derrière Géant Casino). Au programme, cha-cha-cha et rock and roll jive.
ladepeche.fr — Decazeville. Cha-cha-cha et rock and roll à Concept Form - ladepeche.fr -
Amidst a maelstrom of global concerns, the seemingly innocuous practice of military chaff deployment has drawn scrutiny. This routine defense measure involves releasing aluminum-coated fiberglass and plastic particles into the air to confuse enemy radar systems. However, the potential risks to human health and the environment from these minuscule fragments are far from negligible.
BNN — Unseen Hazards of Military Chaff and Its Impact on Health and Environment Amidst Global Concerns -
According to the Naval Health Research Center, chaff consists of aluminum-coated glass fibers and does not pose significant environmental hazards.
FOX Weather — Dallas-area radar detects military chaff traveling through the sky | Fox Weather -
Photo 1: R-23-04 at 81 to 90 metres (Richards Breccia) - Coarse aggregates and veinlet fills of chalcopyrite + pyrite + pyrrhotite ± chalcocite in altered breccia.
GlobeNewswire News Room — Copper Road Resources Intersects Broad Zones of Visible -
Figure 2 AM-23-004 from 28.55 – 34.25 m exhibiting disseminations and veining of pyrite, chalcopyrite and bornite mineralization within intensely altered granodiorite
Yahoo Finance — GSP Resource Corp. 2023 Drill Program Intersects Sulphide Mineralization at Alwin Mine Copper-Silver-Gold Project -
On the track, cinematic strings dissolve into a punchy beat as Tones And I’s vocals rise from intimate verses towards a chantable chorus punctuated by a proclamation, “I will be the greatest.” The song layers eloquent orchestration over glitchy production and rich piano as her uplifting vocals meet this ebb and flow with power and passion. Be on the lookout for an equally emotional and arresting music video to accompany “The Greatest.”
Prelude Press — Tones And I The Greatest -
“LimeLight” captivates listeners with its ominous piano loop and accenting bells that create an intriguing musical landscape. Masicka’s rapid-fire verses, delivered against the glitchy beat, leave an unforgettable impact, while the chantable chorus urges listeners to “Keep shining.”
Jamaicans.com News and Events — Jamaican Dancehall Phenom Masicka Releases New Single “Limelight” Today -
With sets packed full of danceable pop, chantable anthems, Joy Division throwbacks and much, much more, you don’t want to miss New Order when they’re in town. And that’s exactly where they are this week: the Manchester band are in London for a huge show at the O2 Arena in Greenwich.
Time Out London — New Order at London O2 Arena: Timings, Potential Setlist & Tickets For Concert -
Inspiré des diverses formes de guitares anciennes apportées par les colons espagnols au XVIe siècle, le charango est un instrument traditionnel utilisé par les peuples autochtones des Andes. Originaire de Bolivie et du Pérou, ce petit instrument au son clair et puissant est souvent surnommé le “luth des Andes”. Essentiellement joué par les musiciens folkloriques andins, l’un des rythmes les plus populaires, El Condor Pasa, a été repris par le groupe Simon and Garfunkel dans les années 1970.
Konbini - Musique, cinéma, sport, food, news : le meilleur de la pop culture — Les instruments rares et atypiques utilisés par Stromae dans son nouvel album Multitude -
The Delhi High Court has held that AO did not have the tangible material on record that could have persuaded him to form the belief that income, otherwise chargeable to tax, had escaped assessment.The bench of Justice Rajiv Shakdher and Justice Girish Kathpalia, the AO, did not employ diligence while triggering the reassessment proceedings against the petitioner or assessee. Because AO...
AO Lacked Tangible Material To Form A Belief That Income, Chargeable To Tax Had Escaped Assessment: Delhi High Court Quashes Reassessment Notice -
Every year, half a million children under five die of diarrhoea globally — but doctors and pharmacists often don’t prescribe a cheap lifesaving treatment for the condition. A large Indian study suggests that this happens because prescribers don’t think that their patients want the therapy.
Why a cheap, effective treatment for diarrhoea is underused -
BENGALURU: Sculptor Arun Yogiraj, the creator of the Ram Lalla idol installed at the Ram temple in Ayodhya, revealed the silver hammer and the golden chisel used to carve Ram Lalla’s eyes in Ayodhya.
Public Tv English — Sculptor Arun shares photo of silver hammer, golden chisel used to chisel Ram Lalla's eyes - Public TV English -
Liu S, Shao S, Li L, Cheng Z, Tian L, Gao P, et al. Substrate-binding specificity of chitinase and chitosanase as revealed by active-site architecture analysis. Carbohydr Res. 2015;418:50–6.
Nature — Widespread occurrence of chitinase-encoding genes suggests the Endozoicomonadaceae family as a key player in chitin processing in the marine benthos | ISME Communications -
Regarding chitinase production, the most potent isolates (Fig. 2a) were characterized molecularly based on 16SrDNA gene fingerprint as Streptomyces mutabilis Nof21 (accession number: OP647097), Streptomyces variabilis Am1 (accession number: OP647095), and Streptomyces roietensis Bat2 (accession number: OP647096).
Nature — Screening for chitin degrading bacteria in the environment of Saudi Arabia and characterization of the most potent chitinase from Streptomyces variabilis Am1 | Scientific Reports -
On July 7, 2023, Mr. Acuna was sentenced to a $12,000 fine and a two-year probation order prohibiting the possession of sodium chlorite and the advertisement, sale, and manufacturing for sale of any unauthorized health products, including drugs and natural health products.
Calgary man receives $12,000 fine and two-year probation order for selling “Miracle Mineral Solution”, an unauthorized drug - Canada.ca -
Then came the civilianisation project, which followed a Government edict to Defence to trim $350 million-$400 million from its budget by 2014/15. This came after a "value for money" review led by former State Services Commission head Rod Deane, and a Government white paper in 2010 which proposed a suite of cuts and savings. Part of the drive was for Defence to retain the savings to put towards the huge upcoming costs of ships and other equipment due for replacement in the next 15 years.
NZ Herald — The little navy that couldn't - New Zealand News - NZ Herald -
Comparison of the number of flower and cladode buds between sexual forms of Opuntia robusta in central Mexico. We fitted a generalized linear model with negative binomial error distribution. Different letters denote significant differences between the mean values at P ≤ 0.05.
Nature — Impact of the female and hermaphrodite forms of Opuntia robusta on the plant defence hypothesis | Scientific Reports -
Researchers found that the control and late-maturity cladode groups demonstrated significant improvements to several parameters of bone health compared to the early-maturity cladode groups. The control group, the 100-day cladode group, and the 135-day cladode group all demonstrated significantly higher failure load of femurs than the early-maturity groups, and those three groups also had the highest calcium content in the femurs.
Nutritional Outlook — Calcium from Prickly-Pear Plant May Improve Bone Health, Animal Study Suggests -
As Mr. Biden, Mr. Austin, Mr. Blinken, Mr. Guterres, Mr. Ruto, and Mr. Henry certainly know, there are no legal (not even humanitarian) grounds to claim the bogus reciprocity arrangement being promoted, in violation of Kenya’s National Police Service Act. In addition, UN Resolution 2699’s specific call for a very familiar year-by-year, ad vitam æternam renewal commitment kills any attempt to claim temporary emergency deployment (see Articles 108 & 109 of the Act governing the matter).
Rezo Nòdwès - Le journal citoyen ! — NEHRO | Kenya’s police deployment to Haiti and the bogus claim of « reciprocity », knowingly and willfully promoted by Ariel Henry, William Ruto, and others, in flagrant violation of the National Police Service Act - Rezo Nòdwès -
He described the spread of fake news as an assault on the security architecture of the country and disclosed that the IGP had ordered the NPF National Cybercrime Centre, to monitor online platforms, and to clamp down on individuals and groups bent on jeopardising Nigeria’s national security
Punch Newspapers — Police vow to clamp down on fake news -
The Israeli police arrested two suspects on Saturday for allegedly spitting on a Christian clergyman in Jerusalem's Old City and cursing at him. The two suspects were interrogated and released to house arrest.
All Israel News — Faith under fire: Two ultra-Orthodox Jews arrested for spitting on Christian clergyman in Jerusalem's Old City | All Israel News -
After they’ve parted ways, each earthworm produces a sheath with its clitellum and shimmies it down its tubular body. The protein-rich ring moves over tiny holes where it gathers eggs and some of the collected sperm.
Earthworm Love is Cuddly ... and Complicated | KQED -
Night crawlers are red or pinkish, slimy and the clitellum bumps out and does not go all the way around.
https://www.wsaw.com — Jumping worms do damage to your soil and plants -
Organize a bathroom closet the right way with our expert tips and tricks
Real Homes — How to organize a bathroom closet | Real Homes -
“The coaptation performed in this first surgery was straight forward and the patient has recovered well.
World first successful nerve repair surgery | Metro South Health -
The goal of Elodie’s heart surgery was to resolve the narrowing of her aorta to ensure good blood flow to the heart. Dr. Hanley described two surgical approaches to repair Elodie’s coarctation of the aorta: one, where he enters through the chest (traditional open-heart surgery), and another, where he goes through the left side—each option carrying different risks.
Healthier, Happy Lives Blog — Girl Faces Open-Heart Surgery With Strength, Humor, and Grace - Stanford Medicine Children’s Health BlogHealthier, Happy Lives Blog -
Herzog, D. P. E., Dohle, E., Bischoff, I. & Kirkpatrick, C. J. Cell communication in a coculture system consisting of outgrowth endothelial cells and primary osteoblasts. BioMed Res. Int. 2014, 1–15 (2014).
Nature — Semipermeable Capsules Wrapping a Multifunctional and Self-regulated Co-culture Microenvironment for Osteogenic Differentiation | Scientific Reports -
Mimicking the change in marine environment, the researchers supplied sterile inorganic nutrients to the established mutualistic coculture of Synechococcus and a diverse bacterial community from their previous study. The two-year-old stable and mutually beneficial relationship buckled but did not break.
EurekAlert! — Marine phytoplankton gets by with a little he | EurekAlert! -
AuntExcPrb calculates or simulates the probability of excluding N aunts from the maternity of a male by using L codominant marker data. Calculations use a formula under the assumption of a haplodiploid species with haploid males and diploid females. Simulations assume either a diploid species (where both males and females are diploid) or a haplodiploid species. The formula and simulations are described in the paper:
AuntExcPrb | ZSL -
Russian forces have made some small advances in eastern Ukraine that brought them closer to the coking and chemical plant, the UK Ministry of Defense says.
dw.com — Ukraine updates: Russia nudges toward Avdiivka coking plant – DW – 11/28/2023 -
India’s steel majors are seeking government intervention to control raw materials prices, primarily iron ore and coking coal.
BusinessLine — Indian steel mills urge government intervention in coking coal price indexing - The Hindu BusinessLine -
The fun-loving brand of colorable indoor play balls exhibits at this year’s show, bringing with it the new STEAM Editions focusing on math, science and art.
Ollyball Bounces Full STEAM Ahead Into the 2023 New York International Toy Fair | Newswire -
“The negative aspects have been addressed as their retail business recovers while their wholesale operations have bottomed out,” said Satoru Matsumoto, an S&P Global Ratings analyst, cautioning the job isn’t finished. “Costs are high, and they are falling short of generating profit commensurable with them. We are continuing to watch that.”
Yahoo Finance — Nomura’s Trading Overhaul Advances as Okuda Plans Buyback